Beilstein J. Org. Chem.2010,6, No. 47, doi:10.3762/bjoc.6.47
increased biological half-life.
Keywords: glycopeptide; glycosylaminoacids; β3-homo-threonine; MUC1 antigens; solid-phase synthesis; Introduction
Glycosylation is the predominant co- and post-translational modification in higher organisms responsible for tailoring and fine-tuning of the activity of
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Graphical Abstract
Figure 1:
Structures of the naturally occurring TN and TF antigens and the targeted Fmoc-β3hThr analogues.